Not only do these bacilli crowd out pathogenic bacteria, but they increase microbial diversity in our gut.Ģ2:15 I asked when we do a stool analysis on our patients, why don’t we see these bacillus strains listed as commensal bacteria? Kiran answered that some of the panels will list bacillus subtilis under dysbiotic flora due to a misunderstanding. Our primitive ancestors were consistently eating dirt since they could not wash their food before they ate it, so they were constantly getting exposed to these bacilli. Then they form spores and leave the body through defecation and then find another host through being eaten in some dirt. They do colonize the gut and adhere to the wall and outcompete bad bacteria, but they only last about 20-21 days. And each of us have a unique set of bacteria strains that we first got from our moms.ġ8:26 Like conventional probiotics, spore based probiotics do not permanently colonize the gut. Many of these strains were first pulled out from a human volunteer 35 years ago and since then, they’ve been growing in a factory and the strain has completely changed and has adapted to life in the factory. But this is not true, since the particular strains of lactobacillus acidophilus in the stores are different than the strains found in your gut. In fact, if you go to Pub Med you’ll find that some of these bacillus strains are the most well-studied of all probiotics.ġ5:32 Kiran explained that it is interesting to note that most people think that the strains like lactobacillus and bifido bacteria that you see in most conventional probiotics are the natural strains found in our guts. Some of the spore-based probiotic strains, like bacillus subtilis, have been used in most of the world (in Europe, Asia, and Latin America) as prescription drugs since 1952 and have thousands of studies on them. Only a few of the bacteria in the soil are bacillus species and have endospores and these are the ones that can survive the trip down our digestive tract and are native to our gut.ĩ:35 If you do a Google search for spore-based probiotics, mostly negative articles come up that claim that they are new and that there are very few studies on them. This is why most other, non-spore-based probiotics are killed by the time they end up in the colon.Ħ:59 The difference between soil based and spore-based probiotics is that most of the bacteria in the soil have no benefit for us in our gut as probiotics. Because these probiotics are encased in a spore, they have the capability to survive through the acid in the stomach and the bile salts and the pancreatic enzymes in the small intestine. Ben Weitz.ĥ:49 When Kiran was researching which strains of probiotics are most effective and have the most research, he kept coming back to the spore-based bacillus species. Kiran Krishnan, microbiologist, talks about the benefits and research on Spore-based Probiotics with Dr. Podcast: Play in new window | Download | Embed
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